TORC2 Antibody

Product: Porcine dynorphin A(1-13)

TORC2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 475 and 500 of human Transducer of Regulated cAMP Responsive Element-Binding Protein (CREB) 2 using the numbering given in entry NP_859066.1 (GeneID 200186).
Clonality
Polyclonal
Host
Rabbit
Gene
CRTC2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunoprecipitation 1-4 ug/mg of lysate
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 24755741)

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Theoretical MW
73 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
TORC2 Lysate (NBL1-09492)
Publications
Read Publications using
NB100-79816 in the following applications:

  • ICC/IF
    1 publication
  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TORC2 Antibody

  • CREB regulated transcription coactivator 2
  • CREB-regulated transcription coactivator 2
  • CRTC2
  • TORC2
  • TORC-2
  • TORC2transducer of regulated cAMP response element-binding protein (CREB) 2
  • Transducer of CREB protein 2
  • Transducer of regulated cAMP response element-binding protein 2

Background

TORC2 (transducer of regulated CREB activity 2) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC1 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. TORC2 has been found to be pivotal to the process of gluconeogenesis. TORC2 is also known as CREB regulated transcription activator 2, and CRTC2.

PMID: 7984289