Claspin Antibody

Product: beta-lactamase-IN-1

Claspin Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 900 and 950 of human Claspin using the numbering given in entry AAG24515.1 (GeneID 63967).
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
CLSPN
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • Immunoprecipitation 2-10 ug/mg of lysate
Application Notes
By Western blot, this antibody recognizes bands around 180 kDa representing Claspin. Also useful for Immunoprecipitation *The investigator should determine the optimal working dilution for a specific application.
Positive Control
HeLa Lysate (NB800-PC1)
Publications
Read Publications using NB100-248.

Reactivity Notes

Human. Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Claspin Antibody

  • claspin homolog (Xenopus laevis)
  • claspin homolog
  • Claspin
  • CLSPN
  • hClaspin
  • MGC131612
  • MGC131613
  • MGC131615

Background

Claspin is a cell cycle regulated protein. It plays a critical role in replication checkpoint control and interacts with the checkpoint proteins ATR and Rad9. It also associates with Chk1, but only following replication stress or other types of DNA damage.

PMID: 21956448