TCF-3/E2A [p Thr355] Antibody Summary
| Immunogen |
A synthetic phospho-peptide, which represented a portion of human E2A immunoglobulin enhancer binder factors E12/E47 around threonine 355 (LocusLink ID 6929).
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| Modification |
p Thr355
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| Predicted Species |
Porcine (100%), Primate (100%), Bovine (100%), Monkey (100%), Equine (100%), Canine (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
TCF3
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Western Blot, where a band should be seen at ~70-80 kDa. *The investigator should determine the optimal working dilution for a specific application.
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| Positive Control |
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| Publications |
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Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, European domestic ferret, African elephant, Small-eared galago, Little brown bat and Northern white-cheeked gibbon.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for TCF-3/E2A [p Thr355] Antibody
- bHLHb21
- bHLHb21TCF-3
- Class B basic helix-loop-helix protein 21
- E2A immunoglobulin enhancer-binding factor E12/E47
- E2A
- E2AKappa-E2-binding factor
- Immunoglobulin enhancer-binding factor E12/E47
- Immunoglobulin transcription factor 1
- ITF1
- ITF1Transcription factor ITF-1
- Kappa-E2-binding factor
- MGC129647
- MGC129648
- Pan2
- TCF-3
- Tcfe2a
- transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- Transcription factor 3
- transcription factor E2-alpha
- VDIR
- VDR interacting repressor
Background
E2A proteins are ubiquitously expressed. They are important transcription factors downstream of the T-cell receptor (TCR) signal that regulate multiple stages of thymocyte development and suppress T-cell lymphoma. Deficiencies in E2A promote age-dependent autoimmune diseases, such as T lymphoma.