FANCI Antibody

Product: Pamapimod

FANCI Antibody Summary

Immunogen
A synthetic peptide mapping to a region between residues 200 and 250 of human KIAA1794/FLJ10719 using the numbering given in TrEMBL entry Q9NVI1 (GeneID 55215).
Clonality
Polyclonal
Host
Rabbit
Gene
FANCI
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2500-1:10000
Application Notes
This antibody can be used for Western Blot. *The investigator should determine the optimal working dilution for a specific application.
Positive Control
HeLa Lysate (NB800-PC9)
Publications
Read Publications using NB300-243.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FANCI Antibody

  • Fanconi anemia group I protein
  • Fanconi anemia, complementation group I
  • KIAA1794FLJ10719
  • Protein FACI

Background

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

PMID: 9357513

FANCI Antibody

Product: Trapidil

FANCI Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1025 and 1075 of human Fanconi anemia, complementation group I using the numbering given in entry NP_060663.2 (GeneID 55215).
Predicted Species
Porcine (100%), Bat (100%), Primate (100%), Equine (100%), Monkey (100%), Canine (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
FANCI
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2 – 10 ug/mg lysate
Publications
Read Publication using NB100-60447.

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset, Crab-eating macaque, Small-eared galago, Little brown bat and Northern white-cheeked gibbon.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FANCI Antibody

  • Fanconi anemia group I protein
  • Fanconi anemia, complementation group I
  • KIAA1794FLJ10719
  • Protein FACI

Background

FANCI is the gene underlying Fanconi anemia complementation group I, a syndrome characterized by a predisposition to cancer, congenital malformations, and pancytopenia. At the cellular level, FANCI is involved in the S and G2 phase DNA damage checkpoint and in the repair of DNA double-strand breaks and cross-links.

PMID: 17113074