GSG2 Antibody

Product: Oxidopamine (hydrobromide)

GSG2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human serine/threonine-protein kinase Haspin (germ cell-specific gene 2) using the numbering given in entry NP_114171.2 (GeneID 83903).
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
GSG2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry 1:100-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 5-10 ug/mg lysate
Application Notes
This antibody is useful for western blot and immunoprecipitation. Although not tested this antibody may be useful in Immunoflourescence/Immunocytochemistry.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Theoretical MW
88 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Gorilla.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GSG2 Antibody

  • EC 2.7.11.1
  • germ cell associated 2 (haspin)
  • Germ cell-specific gene 2 protein
  • Haploid germ cell-specific nuclear protein kinase
  • haspin
  • H-haspin
  • serine/threonine-protein kinase haspin

Background

Hapsin is a serine-threonine protein kinase that was originally identified as a cDNA expressed specifically in mouse testicular germ cells. Haspin associates with the chromosomes, centrosomes, and spindle and is critical for proper chromosome alignment and segregation. Haspin is responsible for the phosphorylation of histone H3 at threonine 3.

PMID: 22178753