FAK Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the C-terminus region of human FAK. The exact sequence is proprietary.
|
| Localization |
Cell junction; focal adhesion; Cell membrane; Peripheral membrane protein; Cytoplasmic side
|
| Marker |
Focal Adhesion Marker
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PTK2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
122 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for FAK Antibody
- EC 2.7.10
- FADK 1
- FADK1
- FADKFAK-related non-kinase polypeptide
- FAK
- FAK1FRNK
- FAKEC 2.7.10.2
- focal adhesion kinase 1
- pp125FAK
- Protein-tyrosine kinase 2
- PTK2 protein tyrosine kinase 2
- PTK2
Background
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq]