Product: Oleanolic acid derivative 1
p53R2 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human p53R2. The exact sequence is proprietary.
|
| Localization |
Cytoplasm; Nucleus
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| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
RRM2B
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for p53R2 Antibody
- EC 1.17.4.1
- MGC102856
- MGC42116
- MTDPS8A
- MTDPS8B
- p53-inducible ribonucleotide reductase small subunit 2 homolog
- p53-inducible ribonucleotide reductase small subunit 2-like protein
- p53R2
- P53R2DKFZp686M05248
- PEOA5
- ribonucleoside-diphosphate reductase subunit M2 B
- ribonucleotide reductase M2 B (TP53 inducible)
- RRM2B
- TP53-inducible ribonucleotide reductase M2 B
Background
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.