TAO Kinase 1 Antibody Summary
| Immunogen |
Synthetic 17 amino acid peptide from C-Terminus of human TAOK1.
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| Specificity |
Human TAOK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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| Predicted Species |
Turkey (100%), Opossum (100%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
TAOK1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
IHC-P: Requires pretreatment with Proteinase K.
|
Reactivity Notes
Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Platypus (100%), Zebrafish (88%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for TAO Kinase 1 Antibody
- EC 2.7.11
- FLJ14314
- hKFC-B
- KIAA1361STE20-like kinase PSK2
- Kinase from chicken homolog B
- MAP3K16EC 2.7.11.1
- MARKKmicrotubule affinity regulating kinase kinase
- PSK2serine/threonine kinase TAO1
- serine/threonine-protein kinase TAO1
- TAO kinase 1
- TAO1serine/threonine protein kinase TAO1 homolog
- Thousand and one amino acid protein 1
Background
TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.