HNF-4 gamma/NR2A2 Antibody Summary
| Immunogen |
Synthetic 17 amino acid peptide from ligand-binding domain of human HNF4G.
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| Specificity |
Human HNF4G. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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| Predicted Species |
Mouse (94%), Rat (94%), Opossum (94%), Hamster (94%), Canine (94%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
HNF4G
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (94%), Panda (94%), Platypus (94%), Equine (88%), Turkey (88%), Chicken (88%), Lizard (82%), Seabass (82%), Pufferfish (82%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for HNF-4 gamma/NR2A2 Antibody
- hepatocyte nuclear factor 4, gamma
- hepatocyte nuclear factor 4-gamma
- HNF4 gamma
- HNF-4 gamma
- HNF4G
- HNF-4-gamma
- NR2A2
- NR2A2Nuclear receptor subfamily 2 group A member 2
- NR2A3
Background
Hepatocyte nuclear factor 4 gamma (HNF4 gamma) is a NR2 Hepatocyte NF4-Like receptor of relatively unknown function. Although HNF4 gamma is structurally related to HNF4 alpha and is expressed together with HNF 4 Alpha in pancreatic islets, it does not play a major role in the etiology of early onset, autosomal dominant, non insulin-dependent type 2 diabetes or maturity-onset diabetes of the young, MODY1. A pseudogene of HNF4 gamma, located on chromosome 13 (13q14.11 – 13q14.3), has been recently identified using a comparative genomics approach. HNF4 gamma expression has been reported human pancreas, kidney, testis, small intestine, and colon. ESTs have been isolated from human tissue libraries, including cancerous brain and colon, and normal brain,stomach, and liver.