Product: Amlodipine (besylate)
Claudin-1 Antibody Summary
| Immunogen |
Synthetic peptide derived from C-terminus of human Claudin-1 peptide.
|
| Localization |
Cell Junction, Cytoplasm, Membrane
|
| Specificity |
This product is specific for Claudin 1
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CLDN1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human and Mouse. Predicted cross-reactivity based on sequence identity: Bovine, Dog, Pig, Rat.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS (pH 7.6) and 1.0% BSA
|
| Preservative |
Sodium Azide
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Claudin-1 Antibody
- claudin 1
- Claudin1
- Claudin-1
- CLD1
- CLDN1
- ILVASCSenescence-associated epithelial membrane protein
- SEMP1
- SEMP1senescence-associated epithelial membrane protein 1
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.