Septin-9 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human SEPT9. The exact sequence is proprietary.
|
| Localization |
Cell membrane
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SEPT9
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rat (89%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1.03 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Septin-9 Antibody
- AF17q25
- FLJ75490
- KIAA0991Ov/Br septin
- MLL septin-like fusion protein MSF-A
- MLL septin-like fusion protein
- MSF1NAPB
- MSFMLL septin-like fusion
- Ovarian/Breast septin
- PNUTL4
- SeptD1
- septin 9
- Septin D1
- septin-9
- SINT1
Background
This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.