Product: GS-7340 (hemifumarate)
ADE2 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human PAICS. The exact sequence is proprietary.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
PAICS
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Chicken (86%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for ADE2 Antibody
- ADE2
- AIR carboxylase
- AIRCADE2H1
- DKFZp781N1372
- MGC1343
- MGC5024
- multifunctional protein ADE2
- PAIS
- phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazolesuccinocarboxamide synthetase
- SAICAR synthetase
Background
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]