NOLA1 Antibody

Product: Mebeverine metabolite Mebeverine alcohol

NOLA1 Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 1a.a. to 217a.a. from NOLA1(a 217a.a. long protein)
Localization
Nuclear
Specificity
Chicken Polyclonal to NOLA1
Clonality
Polyclonal
Host
Chicken
Gene
GAR1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Positive Control
NOLA1 Lysate (NBL1-13712)

Reactivity Notes

This antibody is reactive against Human, mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NOLA1 Antibody

  • GAR1 ribonucleoprotein homolog (yeast)
  • H/ACA ribonucleoprotein complex subunit 1
  • NOLA1member 1 (H/ACA small nucleolar RNPs)
  • Nucleolar protein family A member 1
  • snoRNP protein GAR1

Background

Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex. which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5. instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (“psi”) residues. which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC. the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

PMID: 19649286