Kv7.3 Antibody

Product: TVP1024 (mesylate)

Kv7.3 Antibody Summary

Immunogen
Synthetic peptides corresponding to the middle region of Kv7.3. Immunizing peptide sequence TPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQ.
Clonality
Polyclonal
Host
Rabbit
Gene
KCNQ3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against Kcnq3 and was validated on Western blot.
Publications
Read Publication using NBP1-74102.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS & 2% Sucrose.
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Kv7.3 Antibody

  • BFNC2
  • EBN2
  • KQT-like 3
  • Kv7.3
  • Potassium channel subunit alpha KvLQT3
  • potassium channel, voltage-gated, subfamily Q, member 3
  • potassium voltage-gated channel subfamily KQT member 3
  • potassium voltage-gated channel, KQT-like subfamily, member 3
  • Voltage-gated potassium channel subunit Kv7.3

Background

Kv7.3 is probably important in the regulation of neuronal excitability. It associates with KCNQ2 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.

PMID: 20718751