SERPINB12 Antibody

Product: pGlu-Pro-Arg-MNA

SERPINB12 Antibody Summary

Immunogen
Reacts with residues 260-275 [SHSKDNLKGLEELERK] of the human SERPINB12 protein (NM_080474)
Specificity
Human SERPINB12 protein
Clonality
Polyclonal
Host
Rabbit
Gene
SERPINB12
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
This antibody is useful for Western Blot 1:500-1:1000.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Theoretical MW
46.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SERPINB12 Antibody

  • MGC119247
  • MGC119248
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12
  • serpin B12
  • serpin peptidase inhibitor, clade B (ovalbumin), member 12
  • YUKOPIN

Background

Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. A novel member of the human ov-serpin gene family, SERPINB12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestines. SERPINB12 is an inhibitor of trypsin-like serine proteinases and a new functional member of the human ov-serpin family.

PMID: 12721338