Product: LY 344864 (S-enantiomer)
CLIC3 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human CLIC3. The exact sequence is proprietary.
|
| Localization |
Nucleus, Membrane, Cytoplasm
|
| Predicted Species |
Bovine (90%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CLIC3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Expected cross reactivity based on sequence homology: Mouse (89%) and Rat (88%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.74 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CLIC3 Antibody
- chloride intracellular channel 3
- chloride intracellular channel protein 3
Background
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.