Product: Balsalazide (sodium hydrate)
ZAK Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 700 and 750 of human sterile alpha motif and leucine zipper containing kinase AZK using the numbering given in entry NP_057737.2 (GeneID 51776).
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| Predicted Species |
Primate (100%), Monkey (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ZAK
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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| Theoretical MW |
91 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating macaque and Northern white-cheeked gibbon.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for ZAK Antibody
- AZK
- EC 2.7.11
- EC 2.7.11.25
- HCCS-4
- Human cervical cancer suppressor gene 4 protein
- Leucine zipper- and sterile alpha motif-containing kinase
- mitogen-activated protein kinase kinase kinase MLT
- mixed lineage kinase 7
- mixed lineage kinase with a leucine zipper and a sterile alpha motif
- mixed lineage kinase-related kinase MRK-beta
- Mixed lineage kinase-related kinase
- MLK7
- mlklak
- MLK-like mitogen-activated protein triple kinase
- MLK-related kinase
- MLT
- MLTK
- MRKcervical cancer suppressor gene 4 protein
- pk
- protein kinase
- sterile alpha motif and leucine zipper containing kinase AZK
- Sterile alpha motif- and leucine zipper-containing kinase AZK
Background
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]