ARHGEF11 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 125 and 175 of human PDZ-RhoGEF using the numbering given in entry NP_055599.1 (GeneID 9826).
|
| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ARHGEF11
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
It is not recommended for western analysis.
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for ARHGEF11 Antibody
- DKFZp667F1223
- glutamate transporter EAAT4-associated protein 48
- GTRAP48
- KIAA0380rho guanine nucleotide exchange factor 11
- PDZ-RHOGEF
- Rho guanine exchange factor (GEF) 11
- Rho guanine nucleotide exchange factor (GEF) 11
- RhoA-specific guanine nucleotide exchange factor
- RhoGEF glutamate transport modulator
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq]