Product: MK2-IN-3 (hydrochloride)
Ancient ubiquitous protein 1 Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 426 and 476 of human Ancient Ubiquitous Protein 1 using the numbering given in entry NP_853553.1 (GeneID 550).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
AUP1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Ancient ubiquitous protein 1 Antibody
- ancient ubiquitous protein 1
Background
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signaling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.