KIF14 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 1600 and the C-terminus (residue 1648) of human Kinesin Family Member 14 using the numbering given in entry NP_055690.1 (GeneID 9928).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
KIF14
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
|
| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for KIF14 Antibody
- KIAA0042MGC142302
- kinesin family member 14
- kinesin-like protein KIF14
Background
The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination and speed of the transportation of a variety of important functional molecules, including mRNA. KIFs are involved in neuronal function and development. Kinesin family member 14 (KIF14) is an overexpressed potential oncogene in the 1q region of genomic gain in breast cancer cell lines associated with poor prognosis breast cancer. The gain of chromosome 1q likely reflects oncogene amplification. As such KIF14 may be a potential therapeutic target and indicator of oncogenesis.