Product: Dehydrocholate (sodium)
NCOA5 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human Nuclear Receptor Coactivator 5 (Coactivator Independent of AF-2) using the numbering given in entry NP_066018.1 (GeneID 57727).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
NCOA5
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
||
| Positive Control |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
0.2 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for NCOA5 Antibody
- CIAbA465L10.6
- Coactivator independent of AF-2
- KIAA1637
- NCoA-5
- nuclear receptor coactivator 5
Background
NCOA5 is a nuclear receptor coregulator that can have both coactivator and corepressor functions. It interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. It Is also involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2).