Product: Fluorescein-5-maleimide
USP14 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human USP14. The exact sequence is proprietary.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
USP14
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rhesus Monkey (100%), Chimpanzee (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for USP14 Antibody
- Deubiquitinating enzyme 14
- EC 3.1.2.15
- EC 3.4.19.12
- TGT
- TGTubiquitin carboxyl-terminal hydrolase 14
- tRNA-guanine transglycosylase, 60-kD subunit
- ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- ubiquitin specific protease 14 (tRNA-guanine transglycosylase)
- Ubiquitin Thioesterase 14
- Ubiquitin thiolesterase 14
- ubiquitin-specific processing protease 14
- Ubiquitin-specific-processing protease 14
- Ubp6
- USP14
Background
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]