Product: Chlormadinone (acetate)
Cytochrome P450 17A1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human CYP17A1. The exact sequence is proprietary.
|
| Localization |
Membrane; Single-pass membrane protein
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| Predicted Species |
Monkey (91%), Primate (99%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CYP17A1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (91%), Chimpanzee (99%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
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| Preservative |
0.01% Thimerosal
|
| Concentration |
0.65 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Cytochrome P450 17A1 Antibody
- CPT7
- cyp17
- CYP17A1
- cytochrome p450 XVIIA1
- cytochrome P450, family 17, subfamily A, polypeptide 1
- cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenalhyperplasia
- Cytochrome P450c17
- Cytochrome P450-C17
- EC 1.14.99
- P450C17
- P450C17CYPXVII
- S17AH
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq]