Mitofusin 2 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the N-terminus region of human MFN2. The exact sequence is proprietary.
|
| Predicted Species |
Rat (96%), Bovine (97%), Canine (98%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MFN2
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
86 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Xenopus laevis (82%), Zebrafish (83%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Mitofusin 2 Antibody
- CMT2A
- CMT2A2
- CPRP1
- CPRP1mitochondrial assembly regulatory factor
- EC 3.6.5
- EC 3.6.5.-
- HSG
- KIAA0214hyperplasia suppressor
- MARF
- MFN2
- Mitofusin 2
- mitofusin-2
- Transmembrane GTPase MFN2
Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq]