Product: AZD9056 (hydrochloride)
SERCA3 ATPase Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the N-terminus region of human SERCA3. The exact sequence is proprietary.
|
| Localization |
Nucleus membrane; Endoplasmic reticulum membrane; Sarcoplasmic reticulum membrane
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ATP2A3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
109 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Chicken (88%), Xenopus laevis (92%), Xenopus Tropicalis (91%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
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| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for SERCA3 ATPase Antibody
- adenosine triphosphatase, calcium
- ATPase, Ca(2+)-transporting, ubiquitous
- ATPase, Ca++ transporting, ubiquitous
- Calcium pump 3
- EC 3.6.3
- EC 3.6.3.8
- sarco/endoplasmic reticulum Ca2+ ATPase
- sarco/endoplasmic reticulum Ca2+ -ATPase
- sarcoplasmic/endoplasmic reticulum calcium ATPase 3
- SERCA3calcium-translocating P-type ATPase
- SR Ca(2+)-ATPase 3
Background
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]