HNF-3 beta/FoxA2 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FOXA2. The exact sequence is proprietary.
|
| Localization |
Nucleus
|
| Predicted Species |
Rat (100%), Fish (100%), Chicken (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
FOXA2
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Japanese Medaka (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0) and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for HNF-3 beta/FoxA2 Antibody
- forkhead box A2
- Forkhead box protein A2
- FoxA2
- hepatic nuclear factor-3-beta
- hepatocyte nuclear factor 3, beta
- hepatocyte nuclear factor 3-beta
- HNF3 beta
- HNF-3 beta
- HNF-3B
- HNF-3-beta
- HNF3BTCF-3B
- MGC19807
- TCF3B
- Transcription factor 3B
Background
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.