RPA2 Antibody Summary
| Immunogen |
Full-length human RPA-32 expressed in E. coli.
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| Specificity |
NB100-157 is specific for human RPA32.
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| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Mouse
|
| Gene |
RPA2
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Mouse antiserum with PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Unpurified
|
Alternate Names for RPA2 Antibody
- REPA2
- Replication factor A protein 2
- replication protein A 32 kDa subunit
- Replication protein A 34 kDa subunit
- replication protein A2 (32kD)
- replication protein A2, 32kDa
- RF-A protein 2
- RP-A p32
- RP-A p34
- RPA2
- RPA32
- RPA34
Background
Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase. The middle subunit, RPA-32, is phosphorylated during the S-phase of the cell cycle, in response to DNA damage and during apoptotsis of Jurkat T- lymphocytes.