PDK-1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human PDK1. The exact sequence is proprietary.
|
| Localization |
Mitochondrion matrix
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PDK1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PDK-1 Antibody
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial
- EC 2.7.11
- EC 2.7.11.2
- mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1
- PDK1
- PDK-1
- PDPK1
- PKB kinase
- Pyruvate dehydrogenase kinase isoform 1
- pyruvate dehydrogenase kinase, isoenzyme 1
- pyruvate dehydrogenase kinase, isozyme 1
Background
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. [provided by RefSeq]