Tau Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human Tau. The exact sequence is proprietary.
|
| Localization |
Cytoplasm; cytosol; Cell membrane; Peripheral membrane protein; Cytoplasmic side; cytoskeleton; Cell projection; axon
|
| Marker |
pan-Neuronal Marker
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MAPT
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rat (80%), Mouse (80%), Dog (87%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Tau Antibody
- DDPAC
- FLJ31424
- FTDP-17
- G protein beta1/gamma2 subunit-interacting factor 1
- MAPT
- MGC138549
- microtubule-associated protein tau
- MSTD
- MSTDMAPTL
- MTBT1
- MTBT1Neurofibrillary tangle protein
- MTBT2
- Neurofibrillary tangle protein
- PHF-tau
- PPND
- Tau
- TAUPaired helical filament-tau
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]