Product: Bay 41-4109 (racemate)
PABP Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the N-terminus region of human PABP. The exact sequence is proprietary.
|
| Localization |
Cytoplasm/Nucleus
|
| Predicted Species |
Rat (100%), Monkey (100%), Chicken (100%), Bovine (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PABPC1
|
| Purity |
Protein A purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (100%), Xenopus laevis (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
5.95 mg/ml
|
| Purity |
Protein A purified
|
Alternate Names for PABP Antibody
- PAB1polyadenylate-binding protein 1
- PABP
- PABP-1
- PABP1poly(A) binding protein, cytoplasmic 2
- PABPC2
- PABPL1
- poly(A) binding protein, cytoplasmic 1
- Poly(A)-binding protein 1
- poly(A)-binding protein, cytoplasmic 2
Background
The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]