GNAL Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human GNAL. The exact sequence is proprietary.
|
| Isotype |
IgG
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| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
GNAL
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Zebrafish (87%), Xenopus laevis (90%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.65 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for GNAL Antibody
- Adenylate cyclase-stimulating G alpha protein, olfactory type
- guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide, olfactory typ
- guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide, olfactory type
- guanine nucleotide binding protein (G protein), alpha stimulating activitypolypeptide, olfactory type
- guanine nucleotide-binding protein G(olf) subunit alpha
Background
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP, and most obviously regulate the activity of the best studied effectors. The Gs subfamily of Galpha subunits includes two closely related proteins, Galpha s and Galpha olf, which, respectively, stimulate adenylate cyclase and mediate response to olfactory stimuli.