GPI8 Antibody

Product: (R)-BPO-27

GPI8 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PIGK. The exact sequence is proprietary.
Localization
Endoplasmic reticulum membrane, Single-pass type I membrane protein
Predicted Species
Rat (99%), Porcine (98%), Chicken (95%), Bovine (98%), Zebrafish (90%), Rhesus Macaque (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PIGK
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
293 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.74 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPI8 Antibody

  • EC 3.-
  • GPI transamidase subunit
  • GPI transamidase
  • GPI8 homolog
  • GPI8class K
  • GPI-anchor transamidase
  • hGPI8
  • MGC22559
  • phosphatidylinositol glycan anchor biosynthesis, class K
  • Phosphatidylinositol-glycan biosynthesis class K protein
  • PIG-K

Background

This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

PMID: 6092972