Product: Ruboxistaurin (hydrochloride)
Sodium Potassium ATPase Beta 1 Antibody Summary
| Immunogen |
Peptide with sequence C-KTEISFRPNDPKSYE corresponding to internal region according to NP_001668.1, NP_001001787.1.
|
| Epitope |
C-KTEISFRPNDPKSYE
|
| Marker |
Plasma Membrane Marker
|
| Specificity |
This antibody is expected to recognize both reported isoforms (NP_001668.1; NP_001001787.1).
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
ATP1B1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
|
| Application Notes |
WB: Approx. 48 kDa band observed in rat retina lysates and 50 kDa band in mouse and rat kidney lysates is reported in scientific literature (PMID: 20130120).
|
|
| Publications |
|
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Human, Canine, Bovine, Porcine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Sodium Potassium ATPase Beta 1 Antibody
- adenosinetriphosphatase
- ATP1B
- ATPase, Na+/K+ transporting, beta 1 polypeptide
- Beta 1-subunit of Na(+)
- K(+)-ATPase
- MGC1798
- Na, K-ATPase beta-1 polypeptide
- sodium/potassium-dependent ATPase beta-1 subunit
- Sodium/potassium-dependent ATPase subunit beta-1
- sodium/potassium-transporting ATPase beta-1 chain
- sodium/potassium-transporting ATPase subunit beta-1
Background
Na,K-ATPase is an integral membrane protein complex that hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+ found in most mammalian cells. The enzyme is comprised of an alpha and beta subunit. The alpha-polypeptide has been shown to be the catalytically active subunit, whereas the beta-polypeptide is glycosylated and appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane.