MURF2 Antibody

Product: FT013

MURF2 Antibody Summary

Immunogen
Peptide with sequence C-HIFSFSWLNSLNE corresponding to C-Terminus according to NP_908974.1, NP_908975.1.
Specificity
This antibody is expected to recognize isoforms 1, 3 and 4 (NP_908973.1, NP_908974.1and NP_908975.1 resp.).
Clonality
Polyclonal
Host
Goat
Gene
TRIM55
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 – 0.3 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 85 kDa band observed in human and mouse heart lysates is reported in scientific literature (PMID: 17272810).
Publications
Read Publications using NB100-1196.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat, Canine, Porcine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at [email protected] for more details.

Alternate Names for MURF2 Antibody

  • muRF2
  • MURF-2
  • Muscle-specific RING finger protein 2
  • RING finger protein 29muscle specific ring finger 2
  • RNF29
  • tripartite motif containing 55
  • tripartite motif-containing 55
  • tripartite motif-containing protein 55

Background

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.

PMID: 9277133