Ghrelin/Obestatin Antibody (4B8) Summary
| Immunogen |
GHRL (AAH25791, 1 a.a. ~ 118 a.a) full length recombinant protein with GST tag.MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPEDGGQAEGAEDEMEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK
|
| Localization |
Secreted
|
| Specificity |
GHRL – ghrelin, growth hormone secretagogue receptor ligand
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
GHRL
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Ghrelin/Obestatin Antibody (4B8)
- appetite-regulating hormone
- ghrelin
- ghrelin/obestatin preprohormone
- ghrelin/obestatin prepropeptide
- Ghrelin/Obestatin
- Growth hormone secretagogue
- Growth hormone-releasing peptide
- Motilin-related peptide
- MTLRPgrowth hormone secretagogue receptor ligand
- obestatin
- Protein M46
Background
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.[supplied by OMIM]