ASAH1 Antibody (1A7) Summary
| Immunogen |
ASAH1 (NP_808592, 25 a.a. – 124 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTD
|
| Specificity |
ASAH1 – N-acylsphingosine amidohydrolase (acid ceramidase) 1 (1A7)
|
| Isotype |
IgG3 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
ASAH1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control. It has been used for IHC-P.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for ASAH1 Antibody (1A7)
- ACDase
- ACEC 3.5.1.23
- Acid CDase
- acid ceramidase
- Acylsphingosine deacylase
- ASAH
- FLJ21558
- FLJ22079
- N-acylsphingosine amidohydrolase (acid ceramidase) 1
- N-acylsphingosine amidohydrolase
- PHP
- PHP32N-acylsphingosine amidohydrolase (acid ceramidase)
- Putative 32 kDa heart protein
Background
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq]