4EBP1 Antibody (4F3-H2) Summary
| Immunogen |
EIF4EBP1 (AAH04459, 1 a.a. – 118 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSGGSSCSQTPSRAIPATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI
|
| Specificity |
EIF4EBP1 – eukaryotic translation initiation factor 4E binding protein 1
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
EIF4EBP1
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for 4EBP1 Antibody (4F3-H2)
- 4EBP1
- 4E-BP1
- eIF4E-binding protein 1
- EIF4EBP1
- eukaryotic translation initiation factor 4E binding protein 1,4EBP1,4E-BP1BP-1
- eukaryotic translation initiation factor 4E-binding protein 1
- PHAS-I
- PHAS-IMGC4316
- Phosphorylated heat- and acid-stable protein regulated by insulin 1
Background
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.