Product: Ketanserin (tartrate)
Bad Antibody (3H8) Summary
| Immunogen |
BAD (AAH01901 69 a.a. – 168 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. IRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
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| Specificity |
BAD – BCL2-antagonist of cell death
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| Isotype |
IgG2a Lambda
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
BAD
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Bad Antibody (3H8)
- Bad
- BBC2
- BBC6
- bcl2 antagonist of cell death
- BCL2-antagonist of cell death protein
- BCL2-associated agonist of cell death
- Bcl-2-binding component 6
- BCL2-binding component 6
- BCL2-binding protein
- BCL2L8
- Bcl2-L-8
- BCL2L8bcl2-L-8
- Bcl-2-like protein 8
- BCL-X/BCL-2 binding protein
- Bcl-XL/Bcl-2-associated death promoter
Background
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.