TGF beta induced factor 2 Antibody (5G1) Summary
| Immunogen |
TGIF2 (NP_068581, 131 a.a. ~ 237 a.a) partial recombinant protein with GST tag.SMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGSPTGGLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENP
|
| Specificity |
TGIF2 (5G1)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TGIF2
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TGF beta induced factor 2 Antibody (5G1)
- homeobox protein TGIF2
- TGF(beta)-induced transcription factor 2
- TGF-beta-induced transcription factor 2,5-TG-3-interacting factor 2,5-TG-3 interacting factor 2
- TGFB-induced factor 2 (TALE family homeobox)
- TGFB-induced factor 2
- TGFB-induced factor homeobox 2
- transcription growth factor-beta-induced factor 2
Background
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.