CBX1 Antibody (4E12)

Product: Roflumilast Impurity E

CBX1 Antibody (4E12) Summary

Immunogen
CBX1 (NP_006798, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
CBX1 – chromobox homolog 1 (HP1 beta homolog Drosophila ) (4E12)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CBX1
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CBX1 Antibody (4E12)

  • CBXM31HP1-BETA
  • chromobox homolog 1 (Drosophila HP1 beta)
  • chromobox homolog 1 (HP1 beta homolog Drosophila )
  • chromobox homolog 1
  • chromobox protein homolog 1
  • Heterochromatin protein 1 homolog beta
  • heterochromatin protein 1-beta
  • heterochromatin protein p25 beta
  • Heterochromatin protein p25
  • HP1 beta homolog
  • HP1 beta
  • HP1Hsbeta
  • HP1Hs-beta
  • MOD1
  • Modifier 1 protein
  • p25beta

Background

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

PMID: 20357934