Cdc14A Antibody (2C12) Summary
| Immunogen |
CDC14A (NP_003663 431 a.a. – 530 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPE
|
| Specificity |
CDC14A – CDC14 cell division cycle 14 homolog A (S. cerevisiae)
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CDC14A
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Cdc14A Antibody (2C12)
- CDC10 (cell division cycle 10, S. cerevisiae, homolog)
- CDC14 cell division cycle 14 homolog A (S. cerevisiae)
- CDC14 cell division cycle 14 homolog A
- cdc14
- Cdc14A1
- Cdc14A2
- dual specificity protein phosphatase CDC14A
- EC 3.1.3.16
- EC 3.1.3.48
- hCDC14
Background
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.