TRIM25 Antibody (5C3) Summary
| Immunogen |
TRIM25 (NP_005073 211 a.a. – 310 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SQINGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEK
|
| Specificity |
TRIM25 (5C3)
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TRIM25
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF, IHC-P and ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TRIM25 Antibody (5C3)
- EC 6.3.2.19
- EC 6.3.2.n3
- EFPZ147
- Estrogen-responsive finger protein
- RING finger protein 147
- RNF147E3 ubiquitin/ISG15 ligase TRIM25
- tripartite motif containing 25
- tripartite motif-containing 25
- Tripartite motif-containing protein 25
- Ubiquitin/ISG15-conjugating enzyme TRIM25
- zinc finger protein 147 (estrogen-responsive finger protein)
- Zinc finger protein 147
- zinc finger protein-147
- ZNF147tripartite motif protein TRIM25
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.