DAX1/NR0B1 Antibody (1F10) Summary
| Immunogen |
NR0B1 (NP_000466 361 a.a. – 470 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
|
| Specificity |
NR0B1 – nuclear receptor subfamily 0, group B, member 1 (1F10)
|
| Isotype |
IgG3 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NR0B1
|
| Purity |
Ascites
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate for WB. It has been used for IF and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Ascites
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for DAX1/NR0B1 Antibody (1F10)
- AHC
- AHCDSS
- AHCH
- AHX
- DAX1
- DAX1DAX-1
- dosage-sensitive sex reversal
- DSS-AHC critical region on the X chromosome protein 1
- GTD
- HHG
- NR0B1
- NROB1
- nuclear hormone receptor
- Nuclear receptor DAX-1
- nuclear receptor subfamily 0 group B member 1
- nuclear receptor subfamily 0, group B, member 1
Background
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.