Product: NH4-KLGADTDGEQDQHMTYGGQ-COOH
Bag-1 Antibody (4E2.) Summary
| Immunogen |
BAG1 (NP_004314 241 a.a. – 345 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQETERLQSTNFALAE
|
| Specificity |
BAG1 – BCL2-associated athanogene
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
BAG1
|
| Purity |
IgG purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Bag-1 Antibody (4E2.)
- BAG family molecular chaperone regulator 1
- Bag1
- Bag-1
- Bcl-2 associating athanogene-1 protein
- Bcl-2-associated athanogene 1
- BCL2-associated athanogene
- Bcl-2-binding protein
- glucocortoid receptor-associated protein RAP46,46-KD
- HAP
- RAP46
Background
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.