Dnmt2 Antibody (1E12.) Summary
| Immunogen |
DNMT2 (AAH47733, 1 a.a. – 391 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFHHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLYILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVEEKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE
|
| Localization |
Nuclear
|
| Specificity |
DNMT2 – DNA (cytosine-5-)-methyltransferase 2
|
| Isotype |
IgG1 Lambda
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TRDMT1
|
| Purity |
IgG purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate, transfected lysate and recombinant protein for WB. It has been used for IF and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Dnmt2 Antibody (1E12.)
- DMNT2
- DNA (cytosine-5-)-methyltransferase 2
- DNA (cytosine-5)-methyltransferase-like protein 2
- DNA methyltransferase homolog HsaIIP
- DNA methyltransferase-2
- DNA MTase homolog HsaIIP
- DNMT2
- EC 2.1.1
- EC 2.1.1.29
- M.HsaIIP
- MHSAIIP
- PUMET
- RNMT1
- tRNA (cytosine-5-)-methyltransferase
- tRNA aspartic acid methyltransferase 1
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.