SETDB1 Antibody (4A3) Summary
| Immunogen |
SETDB1 (NP_036564, 2 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFY
|
| Specificity |
SETDB1 – SET domain, bifurcated 1 (4A3)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
SETDB1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence and ELISA.
|
Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SETDB1 Antibody (4A3)
- ERG-associated protein with SET domain
- ESETEC 2.1.1.43
- H3-K9-HMTase 4
- Histone H3-K9 methyltransferase 4
- histone-lysine N-methyltransferase SETDB1
- histone-lysine N-methyltransferase, H3lysine-9 specific 4
- KG1T
- KIAA0067H3-K9-HMTase4
- KMT1EERG-associated protein with a SET domain, ESET
- Lysine N-methyltransferase 1E
- SET domain bifurcated 1
- SET domain, bifurcated 1
Background
The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and Enhancer of zeste proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.[supplied by OMIM]