MCCC2 Antibody (2B3)

Product: Cabozantinib

MCCC2 Antibody (2B3) Summary

Immunogen
MCCC2 (NP_071415, 456 a.a. ~ 564 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
MCCC2 – methylcrotonoyl-Coenzyme A carboxylase 2 (beta) (2B3)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MCCC2
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MCCC2 Antibody (2B3)

  • 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
  • MCCase subunit beta
  • MCCBEC 6.4.1.4
  • methylcrotonoyl-CoA carboxylase 2 (beta)
  • methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
  • mitochondrial
  • non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase

Background

This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq]

PMID: 25948274