TIMM8A Antibody (2F11) Summary
| Immunogen |
TIMM8A (NP_004076, 9 a.a. – 97 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AAGLGAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD
|
| Specificity |
TIMM8A – translocase of inner mitochondrial membrane 8 homolog A (yeast)
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TIMM8A
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TIMM8A Antibody (2F11)
- DDP1deafness/dystonia peptide
- DDPMGC12262
- Deafness dystonia protein 1
- DFN1
- mitochondrial import inner membrane translocase subunit Tim8 A
- MTSTIM8
- TIM8A
- translocase of inner mitochondrial membrane 8 (yeast) homolog A
- translocase of inner mitochondrial membrane 8 homolog A (yeast)
- X-linked deafness dystonia protein
Background
This translocase has similarity to yeast mitochondrial proteins that are involved in the import of metabolite transporters from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Deafness Dystonia Syndrome (MTS/DFN-1) and it is postulated that MTS/DFN-1 is a mitochondrial disease caused by a defective mitochondrial protein import system.