TR4/NR2C2 Antibody (2A5) Summary
| Immunogen |
NR2C2 (NP_003289, 43 a.a. – 152 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKTDVQRPQVVEYCVVCGDKASGRHYGAVS
|
| Localization |
Nuclear
|
| Specificity |
NR2C2 – nuclear receptor subfamily 2, group C, member 2
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NR2C2
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for IHC-P, RNAi Validation and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TR4/NR2C2 Antibody (2A5)
- hTAK1
- NR2C2
- Nuclear hormone receptor TR4
- nuclear receptor subfamily 2 group C member 2
- nuclear receptor subfamily 2, group C, member 2
- Orphan nuclear receptor TAK1
- Orphan nuclear receptor TR4
- TAK1
- TAK1TR4TR2R1
- Testicular receptor 4
- TR4 nuclear hormone receptor
- TR4
Background
TR4 (TAK1, NR2C2) is an orphan nuclear receptor. TR4 was originally cloned from lymphoblastoma Raji cells or mouse brain cDNA library. No ligand has been reported. Northern blot shows TR4 is transcribed as a 9kb mRNA in many tissues and as a 2.8kb mRNA in testis, mainly in spermatocytes. TR4 has two isoforms called TR4alpha1 and TR4 alpha2,which differ in 19 amino acids coded by two separate exons. Both products translated from the 9kb transcript are ubiquitously expressed. Since TR4 binds to the same elements for the RAR-RXR or TR-RXR heterodimers, TR4 may have an inhibitory effect for retinoic-acid mediated transactivation.