PTK7/CCK4 Antibody (4F5) Summary
| Immunogen |
PTK7 (NP_002812, 36 a.a. – 145 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQ
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| Specificity |
PTK7 – protein tyrosine kinase 7
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| Isotype |
IgG2b Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
PTK7
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.
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| Positive Control |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PTK7/CCK4 Antibody (4F5)
- CCK4
- CCK-4
- CCK4Colon carcinoma kinase 4
- colon carcinoma kinase-4
- Protein-tyrosine kinase 7
- Pseudo tyrosine kinase receptor 7
- PTK7 protein tyrosine kinase 7
- PTK7
- Tyrosine-protein kinase-like 7
Background
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.